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ERIC Number: EJ555518
Record Type: CIJE
Publication Date: 1997
Pages: N/A
Abstractor: N/A
Reference Count: N/A
ISBN: N/A
ISSN: ISSN-0895-8017
Dissociation of POMC Peptides after Self-Injury Predicts Responses To Centrally Acting Opiate Blockers.
Sandman, Curt A.; Hetrick, William; Taylor, Derek V.; Chicz-DeMet, Aleksandra
American Journal on Mental Retardation, v102 n2 p182-99 Sep 1997
This study investigated whether blood plasma levels of pro-opiomelanocortin-derived (POMC) peptides, beta-endorphin-like activity, adrenocorticotrophic hormone, and adrenal cortisol immediately after self injurious behavior (SIB) episodes predicted subsequent response to an opiate blocker in 10 patients with mental retardation. Results suggest that changes in the hypothalamic-pituitary-adrenal axis after SIB may predict differences in individual patient responses to opiate blockers. (Author/DB)
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: Researchers
Language: English
Sponsor: N/A
Authoring Institution: N/A