ERIC Number: EJ555511
Record Type: CIJE
Publication Date: 1997
Reference Count: N/A
ApoE Genotype and Alzheimer's Disease in Adults with Down Syndrome: Meta-Analysis.
Prashner, V. P.; Chowdhury, T. A.; Rowe, B. R.; Bain, S. C.
American Journal on Mental Retardation, v102 n2 p103-10 Sep 1997
ApoE gene polymorphism was examined in 100 adults with Down syndrome with and without dementia (Alzheimer's disease) and 346 control subjects. Additionally, a meta analysis of studies (total N=480 subjects) was performed. Results indicated a similar incidence of the gene across groups but subjects with the allele tended to an earlier onset of dementia. (Author/DB)
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A