ERIC Number: EJ467040
Record Type: CIJE
Publication Date: 1993
Epilepsy in Down Syndrome: Clinical Aspects and Possible Mechanisms.
Stafstrom, Carl E.
American Journal on Mental Retardation, v98 suppl p12-26 1993
This review examines clinical aspects of seizures among individuals with Down's syndrome and explores possible mechanisms by which the trisomy 21 brain may generate seizures. Evidence suggests an interplay between pathologically hyperexcitable membrane properties, altered neuronal structure, and abnormal inhibitory neurotransmission. (Author/JDD)
Publication Type: Journal Articles; Information Analyses
Education Level: N/A
Authoring Institution: N/A
Note: Theme Issue: Epilepsy and Mental Retardation.