ERIC Number: EJ398276
Record Type: CIJE
Publication Date: 1989
Reference Count: 0
Concepts in Biochemistry: Chemical Synthesis of DNA.
Caruthers, Marvin H.
Journal of Chemical Education, v66 n7 p577-80 Jul 1989
Outlines the chemistry of the rapid synthesis of relatively large DNA fragments (100-200 monomers each) with yields exceeding 99 percent per coupling. DNA synthesis methodologies are outlined and a polymer-supported synthesis of DNA using deoxynucleoside phosphoramidites is described with structural formulas. (YP)
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: Teachers; Researchers; Practitioners
Authoring Institution: N/A