The aim of study is to develop a valid and reliable scale in order to determine problems encountered by teachers in distance education process. Survey research method was used in the study. The sample of research consists of 411 teachers working in different branches and recitation with distance education at the 2019-2020 academic years. In this study, it was used teachers' problems determination scale consist of 47 items as a data collection tool. In order to validity of the scale, content, construct and face validity was examined. Besides, the cronbach alpha coefficient was calculated for the reliability study. Expert opinion was taken for the content and face validity, and exploratory and confirmatory factor analysis was applied for construct validity. As a result of the exploratory factor analysis, thirteen items were removed and the scale consists of five-factor was confirmed by confirmatory factor analysis. As a result of confirmatory factor analysis, it was calculated values of RMSEA 0.046, GFI 0.83, CFI 0.93 and IFI 0.92. Besides Cronbach alpha internal consistency reliability coefficient of the scale was found 0.892. As a result, a valid and reliable scale consisting of 34-items was developed to determine problems encountered by teachers in distance education process.