"Dikos Nitsaaígíí-19" or COVID-19 has threatened the lives of people of color and Indigenous communities at a higher rate. Across the Navajo reservation, these emergencies have motivated Diné communities to step up and help their people as quickly as possible by distributing care packages to families; providing computers, laptops, free internet access, and food packages; or contributing through research, science, and contact tracing efforts. As this article demonstrates, Diné College was among the first institutions of higher education nationwide to implement a comprehensive approach in response to the COVID-19 pandemic. Major universities soon afterwards used Diné College as a model on steps to take. Moreover, Diné College medical scientists were at the forefront of medical research to study and understand the pathophysiology of COVID-19 and why Native peoples are especially prone to the disease. They also investigated the best methodologies of treatment. Indigenous and other minority medical scientists and clinicians quietly led the fight against COVID-19, as Indigenous administrators set the example on how to respond to the pandemic.