There is a disparity in the number of adults from minority populations employed in STEM careers. In order to increase the interest of at-risk high school students in the STEM field in Queens, NY, an immersive summer biotechnology boot camp was developed. Fifty-five predominantly minority and female students completed the summer boot camp over a three-year period. Students learned about molecular biology, conducted modern biotechnology techniques, detected genetically modified foods sourced from their own homes, created a presentation, and were rewarded with Barnes and Noble gift cards. They then took a survey to reveal their thoughts on the program and their likelihood of pursuing a degree in the STEM field before and after the workshop. Participants became more confident in their science and math skills and indicated they were more likely to complete a STEM degree. Overall, high school students enjoyed the hands-on self-discovery aspect of the project. Many indicated that they became more interested in STEM, which could help increase the number of college entry-level minority students interested in STEM fields.