This article spotlights Colorado and Rhode Island's collaboration efforts on the Keeping Children and Families Safe Act (PL 108-36, 2003), which reauthorized the Child Abuse Prevention and Treatment Act (CAPTA, 2018) and Part C of the Individuals With Disabilities Education Act (IDEA, 2018). These two key pieces of federal legislation require collaboration between state early intervention systems for infants and toddlers with disabilities and their families and welfare programs that focus on prevention and treatment of child abuse and neglect to be effective. From these state examples, we highlight both barriers to and facilitators of successful collaboration across the two programs.