This paper provides an overview of virtue development in the training of Catholic Sisters in Africa and showcases how virtue attainment positions them to be exceptional leaders that promote advances in the state of education in Africa. Additionally, the authors briefly discuss the role of the African Sisters Education Collaborative (ASEC), an international nonprofit organization, in the strengthening of this population's leadership abilities. Three success stories are presented which demonstrate how the education-related work of Catholic Sisters in Africa across traditional and nontraditional settings, is catalyzing positive change in communities and contributing to the United Nations Sustainable Development Goals (SDGs) in Africa.