The authors examined whether perceptions of self-esteem, coping self-efficacy, and emotional intelligence could significantly predict the presence of depressive symptomatology among a sample of 146 Hispanic first-year college students (53 men, 93 women). The results of a sequential multiple linear regression analysis indicated the 3 predictor variables contributed 43.3% of the variance noted in students' reporting of depression symptoms through their Patient Health Questionnaire-9 (Spitzer et al., 1999) scores. The authors discuss implications for future research and provide recommendations for college counseling practice.