Ischemic preconditioning (IPC) has recently been experimented with the hypothesis that it can acutely improve exercise performance. IPC's ergogenic effects have been a novel approach to improve anaerobic power and sprint performances. Since the beneficial effects of the underlying mechanisms on anaerobic power have not been clearly understood, the results obtained from different approaches are not sufficient to reach a clear opinion. The purpose of this study was to determine the effect of IPC on anaerobic power and capacity in the physically active students to provide new findings to the literature. A randomized crossover order, twenty-four physically active male students voluntarily participated in this study. Students completed familiarization before pretest intervention and measurements. They performed a cycle ergometer Wingate 30s protocol resistance with 7.5% bodyweights in IPC and control conditions. The IPC protocol was performed at 220 mmHg, 5 min, 3 times as ischemia interspersed with 5 min of reperfusion. Participants were applied pre and post-test to elicit the effects of IPC on anaerobic performance. Paired sample T-Test was used to determine differences between pre and post-tests. All statistical procedures processed by using the significance level at p < 0.05. The response to IPC treatment did not change anaerobic power and capacity performance outputs (PP t = 0.064, p = 0.95; MP t = -0.151, p = 0.881; PD % t = -0.328 p = 0.746). The application of IPC has not improved significantly any parameters of anaerobic performance. However, non-significant IPC effect on post-exercise lactate level to the extent of 15.32% (t = 1.43, p = 0.17) appeared.