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ERIC Number: EJ1253688
Record Type: Journal
Publication Date: 2020-May
Pages: 5
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Variable Temperature NMR Experiment Studying Restricted Bond Rotation
Huggins, Michael T.; Kesharwani, Tanay; Buttrick, Jonathan; Nicholson, Christopher
Journal of Chemical Education, v97 n5 p1425-1429 May 2020
Nuclear magnetic resonance (NMR) spectroscopy has become a cornerstone tool for studying a variety of molecular features in advanced chemistry laboratories. In this experiment, students prepare a pyrrole-[beta]-amide via a one-pot, three-step synthesis and use NMR spectroscopy to confirm its molecular structure. In addition, variable temperature (VT) [superscript 1]H NMR spectroscopy is used to study the dynamic amide bond, a functional group with restricted rotation about the C-N bond. The VT NMR data allow the students to determine the coalescence temperature associated with the slow equilibrium at room temperature and the corresponding energy barrier (delta G?) for the restricted rotation about the C-N bond.
Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Evaluative
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A