As the ongoing evolution in the higher education sector changes the roles of universities, entrepreneurial practices become more prominent in their agendas. The literature on academic entrepreneurship focuses predominantly on the commercialization of research and less on other intrapreneurial activities--namely those performed by non-academic employees. To fill this gap, this study aims to provide a comprehensive understanding of the factors that influence universities' faculty members and non-academic staff to engage in intrapreneurial activities. The article analyzes Latvian university employees' perceptions of 13 organizational, individual, and environmental factors and how they influence intrapreneurial behavior. Regarding the organizational factors, the results show that higher trust in managers, more available resources for innovative ideas, less formal rules and procedures, and greater freedom in decision-making can lead to higher levels of intrapreneurial behavior. With regard to individual factors, intrapreneurial behavior is associated with an employee's initiative, but is not correlated with risk-taking and personal initiative. As to external factors, while environmental munificence is positively correlated with innovativeness, dynamism and unfavorable change influence employees' engagement in intrapreneurial activities.