Aim: To identify the prevalence and correlates of burnout among research administrators. Background: Research administration is characterized by increasing government regulation, hyper-competitiveness, institutional management of growing complexity, and changing economic conditions. However, there is a lack of research on burnout among research administrators. Methods: A cross-sectional survey was conducted among 2,416 research administrators from four associations in Australia, Canada, the U.K, and the U.S. between October 2018 and January 2019. An online questionnaire was used for data collection. Burnout and workplace factors were measured using the Copenhagen Burnout Inventory and Copenhagen Psychosocial Questionnaire II. respectively. Results: The prevalence of high personal burnout, work-related burnout, and client-related burnout was 68.3%, 60.0%, and 37.0%, respectively. Gender, considered leaving the profession, average working hours/week, self-rated health, job satisfaction, quantitative demands, tempo (work pace), influence at work, predictability, recognition, role clarity, quality of leadership, work-family conflict, justice and respect, vertical trust, threats of violence, and bullying were associated with all three forms of burnout among research administrators. Conclusion: Burnout is common among research administrators. Research organizations are responsible for providing healthy work environments to ensure positive client, research administrator, and organizational outcomes. Future research is required to examine workplace approaches to improving the psychosocial work environment.