Sociological research has demonstrated a link between moving during adolescence and depressive symptoms. In addition, research has documented an inverse association between social support and depressive symptoms. One of the consequences of moving during adolescence is the disruption of social support systems. This suggests that social support may play an important role in the link between moving in adolescence and depressive symptoms, but few studies have explored this possibility. Drawing on data from the National Longitudinal Study of Adolescent to Adult Health and using structural equation models to address measurement error and test mediation, this study finds indirect effects of moving in adolescence on depressive symptoms via certain domains of social support--social support from parents and other adults. Results indicate that the role of social support from teachers and other adults in the link between moving and depressive symptoms merits further investigation.