The 1998 Nuffield Foundation report "Beyond 2000: Science Education for the Future," by Robin Millar and Jonathan Osborne, produced ten recommendations and had a major effect on curriculum development in England, Wales and Northern Ireland. Twenty years after its publication, I pose ten questions for science education. The hope is that these will contribute to the current debate as to what a school science education should consist of and help to lead to an improved science education beyond 2020. [This article is based on a talk given at the 2018 Association for Science Education Annual Conference.]