Lexical stress is recognized in the literature as an important feature in English interactions. For instance, Hahn (2004) and Field (2005) argue that misplaced stress may lead to comprehensibility and ultimately, communication problems. In spite of this acclaimed importance, Jenkins (2000) excludes lexical stress from the Lingua Franca Core (LFC), a set of features that speakers of English as a Lingua Franca should focus on because it does not hinder intelligibility in English communication. This study investigates lexical stress placement by speakers of Ghanaian English. Data consisting of 13 hours of English conversations from 200 Ghanaian university students were analyzed both auditorily and acoustically. Results suggest that similar to outer and expanding Englishes, Ghanaians show fluidity and variation in lexcial stress placement. From the results, it is argued that stress placement appears to be systematic in both outer and expanding circle Englishes, and this does not appear to negatively affect intelligibility in communication in world Englishes. The paper also concludes that it is crucial for all speakers of English to become accustomed to one another's stress patterning in order to sound intelligible and comprehensible in communicating in world Englishes.