There is growing consensus that sexual health education should be inclusive of lesbian, gay, bisexual, transgender and questioning students, and students of various identities on the spectrums of sexuality and gender (LGBTQ+). However, to date, the perspectives of LGTBQ+ teenagers of colour remain under-investigated. Twenty-five in-depth interviews were conducted in 2017-2018 in New York City with LGBTQ+ high school students of colour. Thematic analysis was used to conceptualise the barriers LGBTQ+ students of colour face in learning about sexual health education in school. Students were Latino/a/x (n = 15), non-Latino Black (n = 8), or Asian (n = 2) and self-identified in varied ways in terms of sexuality and gender. Students reported receiving inadequate sexual health education in school due to feeling: 1) unrepresented, 2) unsupported, 3) stigmatised, and 4) bullied. Students filled needed gaps by seeking information and support from external sources. Many students proposed institutional changes or shifts in the school environment to address identified issues, including modifying curricula to incorporate information about consent, mental health and pronouns from the viewpoints of LGBTQ+ teenagers, and to highlight the role of culture, religion and race/ethnicity to represent different experiences. Incorporating the unique experiences of LGBTQ+ students of colour is needed to ensure that all students receive relevant sexual health education.