Within the Sudanese context, education retention and completion are major challenges that have not been seriously and sufficiently addressed. In order to understand in more depth how and why children drop out of primary school in Sudan, six empirical studies were planned as part of an EU-funded national programme focused on primary education and retention in the five states with the lowest basic education completion rates: Blue Nile, Gedaref, Kassala, South Kordofan, and Red Sea. This article discusses the second study (looking at the factors affecting the education and retention of girls in Red Sea State) with the aim of providing a deeper and more comprehensive understanding and analysis of the challenges that girls, in particular, face in accessing schooling, staying in school, and completing the primary cycle (grades 1-8). Specifically, the article provides insights into the processes of dropout and indicators of risk factors that one can use to predict dropout for girls.