We examined children's responses to vignettes depicting a child making one of four friendship transgressions; failing to provide validation, failing to provide help, being an unreliable partner, and betrayal. Twenty elementary students with autism spectrum disorder (ASD) and 21 typically developing (TD) students participated. Children rated emotional responses, the strategies they would use following each transgression, interpretations of transgressions, and goals of their responses. Children with ASD rated sadness lower than TD children, and rated verbal aggression strategies higher than TD children. There were several significant correlations between emotional responses and goals, strategies, and interpretations in the ASD group. Betrayal was considered the most severe transgression. These results will aid researchers aiming to support friendship maintenance in children with ASD.