This study explored the perspectives of medical students from first-in-family (FiF) university backgrounds. Semi-structured interviews focused on steps into, and experiences of medical education, and effects of student identity on social networks. Twenty FiF medical students from one English medical school took part in qualitative interviews. Data was thematically analysed using Bourdieu's forms of capital. This research built on an earlier Australian study as part of an international collaboration. The results showed that secondary school/college financial resources for the application to medical school were variable. Medical school was a financial challenge and paid work impacted on academic learning and students' health. Not having access to medical contacts was a barrier to school work experience and for the medical school application. A lack of cultural capital meant that participants struggled with the medical degree application. Social networks increased at university; however, there was a division along the lines of educational background. Becoming a medical student had an effect on social relationships for many students ambivalent about their new status. Forms of capital were central to participants' experiences. While financial challenges and work experience barriers need addressing, FiF medical student mentors can play an important role in widening participation.