From the evaluation literature related to research and innovation policy, calls have long been made for improved evaluation processes especially where projects and programmes may be evaluated from a systems perspective. Drawing on the literature of innovation systems and innovation for inclusive development (I4ID) this research proposes a state-of-the-art analysis framework, which can be used to evaluate University-driven Technology-based Innovation for Inclusive Development (UTI4ID) projects. In particular, this framework draws on 16 exploratory case studies of UTI4ID that leads to the development of typologies that can be used in future UTI4ID evaluations to better guide such efforts. We thus not only show that advances in the I4ID literature provides an ideal starting point for complexity cognisant evaluations, but also contribute an end-to-end framework to support such evaluations and populate a detailed guide for future UTI4ID projects.