ERIC Number: EJ1221854
Record Type: Journal
Publication Date: 2019
Pages: 20
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-1051-1970
EISSN: N/A
Pharmacokinetic Models for Active Learning of Differential Equations
Shelton, Therese; Laurent, Theresa; Agyemang-Barimah, Beulah
PRIMUS, v29 n7 p742-767 2019
We present adaptable activities for models of drug movement in the human body -- pharmacokinetics -- that motivate the learning of ordinary differential equations with an interdisciplinary topic. Specifically, we model aspirin, caffeine, and digoxin. We discuss the pedagogy of guiding students to understand, develop, and analyze models, progressing in complexity to a system of differential equations. We investigate the effects of parameter values that distinguish various health levels, and dosing that may have toxic effects. Our assignments include modeling in a student-centered, active, and increasingly inquiry-oriented setting through which the mathematics and biology inform and reinforce each other. We include supplemental information regarding inquiry methods, student learning outcomes, a student's commentary about our activities, and support through mathematical communities such as POGIL and SIMIODE.
Descriptors: Equations (Mathematics), Active Learning, Calculus, Pharmacology, Physiology, Concept Formation, Mathematical Models, Inquiry, Higher Education
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Publication Type: Journal Articles; Reports - Descriptive; Guides - Classroom - Teacher
Education Level: Higher Education; Postsecondary Education
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A