Purpose: This paper aims to describe an exploratory research and design process that uses illustrative techniques to bridge the gap between theoretical principles of systems ecology, stakeholder input and a workable physical planning strategy for Ultuna Campus in Uppsala, Sweden. Design/methodology/approach: Stakeholder interviews provide the empirical basis for this exploratory design process, in conjunction with landscape analysis, and review of previous proposals for campus development. Central principles of self-organizing systems are selected and concretized as visionary hypotheses in a physical context. Preliminary design concepts and plans illustrate sustainable systems while supporting new functional programmatic requirements: housing, industry-research collaboration, transportation and community-integrated landscapes. Findings: The result is a proposal based on regenerative landscape design, envisioning campus Ultuna as a coherent whole. Research limitations/implications: A large-scale modern building program is already underway at Ultuna, and rapid urbanization in the surrounding region coupled with projected growth on campus suggests future intensification of university lands. A master plan to be implemented until 2040 is now in the preliminary design phase. Ultuna is home to significant cultural and ecological landscapes, and a holistic approach is called for. Practical implications: Illustrative techniques suggest ways to synthesize knowledge by creating future scenarios that are workable in practice. Social implications: Global challenges call for designs that enhance environmental and human resources and their capacity to regenerate over time. Sustainability objectives are particularly crucial when envisioning university campuses; the environment serves as a laboratory for researchers, teachers, students and residents of the surrounding community. Originality/value: This paper describes an innovative process for bridging ecological principles, stakeholder perspectives and practical design strategies for sustainable campuses.