Student mental health and well-being are increasing concerns in higher education. This exploratory study examined students' learning in a mindfulness programme incorporated into an undergraduate class. Six brief mindfulness-based practices were introduced: mindfulness meditation, walking meditation, body scan, mindful eating, loving-kindness and Tonglen meditation. Fourteen students were interviewed after completion of the course to explore their conceptions and use of mindfulness and other self-care practices. Results of thematic analyses suggest that there were variations in students' adoption of mindfulness-based practices and students' preferred mindfulness techniques. Most participants reported that mindfulness instruction and practice were beneficial but this was not universal; some students reported that mindfulness was 'not for them'. Findings suggest that mindfulness fostered self-reflection, self-awareness and relaxation for many students and incorporating mindfulness at the beginning of class improved the overall quality of discussion and facilitated students' learning. Findings further suggest that students incorporated mindfulness into existing self-care practices that included a variety of other preferred techniques to enhance self-reflection, self-awareness and relaxation. Overall, our findings suggest that students should be helped, through explicit instruction, to develop a 'toolbox' of self-care approaches that may include, but are not necessarily limited to, mindfulness techniques.