ERIC Number: EJ1217794
Record Type: Journal
Publication Date: 2019-Jun
Pages: 10
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0162-3257
EISSN: N/A
Autism with and without Regression: A Two-Year Prospective Longitudinal Study in Two Population-Derived Swedish Cohorts
Thompson, Lucy; Gillberg, Christopher; Landberg, Sara; Kantzer, Anne-Katrin; Miniscalco, Carmela; Barnevik Olsson, Martina; Eriksson, Mats A.; Fernell, Elisabeth
Journal of Autism and Developmental Disorders, v49 n6 p2281-2290 Jun 2019
Two community-based cohorts of children with autism spectrum disorder, examined using similar assessment protocols, were pooled (n = 301) and subdivided according to history of regression. Those with regression (n = 62), 20.5% of the combined cohort, were contrasted with those without regression (n = 241) at first assessment (age range 19-60 months) and at 2-year follow-up on a range of measures. The regression group was significantly more functionally impaired, with regard to intellectual function (p < .001), language development (p < 0.001), and to severity of autism (p < 0.01) at both T1 and T2. Only 14 (23.3%) had a clearly identified underlying etiology [24 (18.6%) in the non-regressive group]. There were no significant differences between those who had regressed 'from normal' and those who had regressed 'from low' functioning.
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Symptoms (Individual Disorders), Severity (of Disability), Intellectual Disability, Language Impairments, Etiology, Young Children, Longitudinal Studies, Cohort Analysis, Foreign Countries
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Sweden
Grant or Contract Numbers: N/A