Long before "fake news" became a catchphrase, misguided beliefs about scientific truths undermined the free exercise of democracy and personal decision-making. Journalistic norms such as providing false balance in the name of "objectivity," deliberate manipulation by vested interests, and the human tendency toward confirmation bias combined to enable the dissemination of damaging misinformation about tobacco, climate change, vaccines, nuclear power, genetically modified foods, and other topics critical to the health and welfare of the modern world. This article examines an innovative new course designed to teach a mixed group of journalism and science, technology, engineering and mathematics (STEM) majors to evaluate expertise and bias, examine data and misrepresentation, and develop evidence-based communication on complex scientific topics. The course covered concepts such as fact-checking, validation, fraud, the "backfire effect," confirmation bias, limitations of the scientific method, conspiracy theories, misuse of statistics, and the role of journalists and scientists as truth-tellers in society. Journalism and science students learned to communicate with each other and with their respective audiences. A series of critical thinking assignments culminated in a final project where students, working in mixed teams, developed an interactive multimedia project communicating a controversial science topic to the public. This interdisciplinary course is offered as one model for teaching science literacy and information literacy to journalism and STEM students.