The nation's leading academic hospitals aspire to being the leader in medical research, but as the role of medical research grows in size and complexity, many departments are left without proper research support or oversight. This research explored the need for a research administrative support program to resolve many of the issues facing faculty researchers in the 21st century. This research resulted in a comprehensive departmental program design for the General Research Administrative Support Program (GRASP) within the Department of Pediatrics at a prominent Midwestern pediatric hospital. The program fosters ongoing communication among all research centers, the department, and the researcher. It will maintain a viable research effort by developing a strategic plan that adheres to the institution's long-term research objectives. The program will create an interactive website that contains educational resources, a research toolkit, and announcements of new funding opportunities. The program office will update faculty regularly on issues with compliance to keep researchers abreast of trends in funded research and requirements, and will create a research mentorship program for new faculty members. The General Research Administrative Support Program (GRASP) will standardize the research support system to foster consistent and reliable administrative support for the modern academic pediatric researcher.