Nonsuicidal self-injury is a significant concern on college campuses. Hence, the authors, the International Consortium on Self-Injury in Educational Settings, offer the current position paper. First, the authors review current research in the field. Next, they discuss considerations for colleges' institutional-wide response to self-injury, including the role of and recommendations for relevant stakeholders (students, residence staff, mental health professionals) who directly and indirectly support students who self-injure. Guidelines for response and suggested resources are also presented.