This research aims to explore the relationship between career decision regret, job satisfaction and life satisfaction as well as determining whether career decision regret significantly predicts job satisfaction and life satisfaction. Having a descriptive research design, the research has employed relational survey model. The population of the research holds a total of 7671 teachers and administrators who work at pre-school education institutions, primary, secondary and high schools located within the central provinces of Kahramanmaras. The research sample consists of 365 participants who have been selected through a random sampling method. The research has deployed "Career Decision Regret Scale", "Job Satisfaction Scale" and "Satisfaction with Life Scale". Independent groups t-test, one-way ANOVA test, Pearson correlation and regression analysis have been used during data analysis. Research results have revealed that teachers' and school administrators' career decision regret is at "a little" level; they have experienced a medium level of general, intrinsic and extrinsic satisfaction; they are at the level of "neither agree nor disagree" in terms of life satisfaction; there is a negative and medium level relation between career decision regret and life satisfaction and between career decision regret and job satisfaction; a significant, positive and medium level relation between job satisfaction and life satisfaction; career decision regret is a significant predictor of job satisfaction and life satisfaction; 25% of the total variance of job satisfaction and 22% of the total variance of life satisfaction level of teachers are explained by career decision regret.