An instruction librarian and a biology professor at a small, urban commuter college campus worked together to provide research instruction to non-science majors in selected hybrid and online biological sciences classes. They collaboratively designed in-class and online learning tools, as well as homework assignments aimed at developing non-science majors' information literacy skills. Through an array of innovative technologies and pedagogical models (including online screencasts, Twitter conversations, and embedded librarianship), they sought to engage non-science majors in the scientific discourse and to encourage them to access and assess reputable online science materials. This study explores the efficacy of their pedagogical partnership.