The purpose of the study was to investigate the relationship between academic self efficacy, ethnic identity and spirituality in African American STEM students. We hypothesize that there will be a significant relationship between three dimensions of spirituality and outcome expectations in African American STEM students and that there will be a significant relationship between outcome expectations and ethnic identity. 165 African American undergraduates in STEM disciplines enrolled at a historically-black university comprised the target population for this study. A regression and correlation analysis revealed that one dimension of religiosity was significantly related to and predicted academic outcome expectations among African American STEM students.