In this age of science, there is a need for rational individuals who are open to innovations to be able to limit and combine information and establish inter-system relationships. Problem solving is considered to be the most important cognitive activity that requires mental effort and will-power. The processes applied in mind when solving a mathematical and chemistry problems are similar. This study was conducted with a total of 50 students studying in the first grade of science teacher education. Two different chemistry problems, which are not routinely given to students, are being investigated and the approaches that science teacher candidates exhibit in solving real-life chemistry problems are desired. It is a descriptive research since an attempt has been made to demonstrate an existing situation in the study. According to the findings, it is seen that most of the candidate teachers are successful in expressing both problems in their own way, but they are less successful in expressing the chemistry knowledge necessary to solve the problem and relating them to the solution.