Background: As a comprehensive measure for children with autism spectrum disorder (ASD), the Psychoeducational Profile -- Third Edition (PEP-3) has been validated and widely used in the United States. This study attempted to investigate the psychometric properties of the Chinese version of the PEP-3 (CPEP-3) Caregiver Report. Method: A total of 455 Chinese children diagnosed with ASD in Hong Kong and their parents participated in the study. Internal consistency, test-retest reliability, content validity, and concurrent validity of the CPEP-3 Caregiver Report were examined. Results: The internal consistency and test-retest reliability of the subtests were good to excellent. Item discrimination and item difficulty findings were satisfactory. The measure also correlated well with the observer-rated Performance Test of the CPEP-3 and the Hong Kong Based Adaptive Behavior Scale. Conclusion: The CPEP-3 Caregiver Report can be used as an objective supplementary assessment tool for early identification and intervention programming for children with ASD in the Chinese context.