Mixed methods research is growing in acceptance and complexity, which translates into significant pedagogical challenges for teaching about mixed methods research. To address this challenge and to contribute to creating a pedagogical culture for teaching research methods, we developed a practically focused conceptual framework for describing the field of mixed methods research and used this framework to structure an Introduction to Mixed Methods Research course. Our socio-ecological framework describes the field of mixed methods within three nested and interacting levels: the mixed methods research process, content, and contexts. The course introduces students to each level and its components and considers how the framework accounts for different perspectives, issues, and debates found within the field. Course evaluations suggest that the new pedagogical approach helps students successfully understand and navigate the complexity and nuances of the mixed methods field, and develop foundational knowledge for designing and implementing a mixed methods study.