Public health relies on sample surveys to monitor the health of populations and investigate factors that contribute to population health and illness. Such investigations require surveying individuals who are selected in ways that support statistical inference to the population. Faced with rising costs and declining participation, survey researchers are exploring economical ways to recruit samples that validly represent larger populations. The current report describes an innovative resource, the Colorado Adult Population Sample--Survey Research Registry, which maintains survey access to respondents from a probability-based state health survey. We describe recruitment and retention strategies, explore representativeness, report several studies that used the registry, and discuss future directions.