Teachers' sense of self-efficacy is crucial for the success of implementation of inclusive education in schools. The Education White paper 6 mandated the District-Based Support Teams (DBSTs) to successfully support teachers to feel more equipped and be competent in their roles to address barriers to learning, which consequently will experience positive self-efficacy beliefs. The purpose of this article is to explore the competencies of the DBST in enhancing teachers' sense of self-efficacy within Full-Service schools. Data were generated by means of interviews using a qualitative approach. Members of the DBST and teachers from the Full-Service schools in two provinces of South Africa participated in this research. The findings revealed that certain factors such as incompetent leadership, inefficient support, unavailability of structured programmes as well as poor communication and cooperation disable DBSTs with respect to enhancing teachers' sense of self-efficacy in various ways. The authors recommend that by addressing these factors teachers' sense of self-efficacy will be enhanced.