The National Eye Institute (2015) reports that by the year 2050, the number of individuals with age-related macular degeneration (AMD) will rise from 2.07 million to 5.44 million. AMD causes central vision loss, which can affect independence in activities such as medication management, meal preparation, and personal finances (Smallfield, Clem & Myers, 2013). Most of these activities require reading, making an inability to read a concern for those with AMD (Hassell, Lamoureaux, & Keeffe, 2006). Font size and style of text may improve reading performance for individuals with low vision. Most recommendations addressing font styles are not evidence based. The aim of this mixed-methods study was to determine the preferred font style of individuals with AMD, and whether a sans-serif, proportionally-spaced font (Arial) or a serif, mono-spaced font (Courier New) improved reading performance for individuals with AMD.