This article discusses key issues in the integration of an intersectionality lens in the developmental sciences and introduces a peer-reviewed thematic journal issue on this topic. We begin by briefly situating the importance of an intersectionality lens within the changing demographics and sociopolitical history in the United States, and within developmental science as a field. We provide a brief overview of recommendations on responsible use of intersectionality in developmental science. We then introduce contributions contained within this volume, and how each contributor grappled with the following question: "How can an intersectionality perspective inform the developmental phenomena of interest and particular developmental theories you draw upon in your area of research?" We end by noting that these contributions offer a collection of manuscripts that aim to increase dialogue among developmental scientists on ways to productively integrate an intersectionality lens in developmental science.