This study focused on the influence of psychosocial factors on job performance of female teachers in Kwara State, Nigeria. The study also examined the variables of age, level of education and length of years in service. The descriptive survey was adopted for the study. A total sample of 400 respondents was selected in Kwara State, using the simple random and purposive sampling techniques. Data were collected using a researcher-designed instrument titled "Influence of Psychosocial Factors on Job Performance Questionnaire" (IPFJPQ). The reliability was ascertained through a test re-test reliability method; this yielded a coefficient of 0.60. ANOVA statistical method was used to analyze the data at 0.05 alpha level. The findings are that the influence of psychosocial factors on job performance of female teachers in Ilorin metropolis is negative; there is no significant difference in the hypotheses tested based on age but, significant differences were found based on level of education, and length of years in service. It was therefore recommended that female teachers should adopt rational management strategies to handle psychosocial factors to improve their job performance. Counsellors should orientate teachers on how to adopt positive approach towards management of psychosocial factors.