Background: Social network analysis (SNA) literature suggests that leaders should be well connected and can be identified through network measurements. Other literature suggests that identifying leaders ideally involves multiple methods. However, it is unclear using SNA alone is sufficient for identifying leaders for higher education change initiatives. We used two sets of data, teaching discussion network data taken at three different times and respondent nominations for leaders, to determine whether these two methods identify the same individuals as leaders. Results: Respondent-nominated leaders have more direct and indirect ties on average than non-leaders, which aligns with the SNA literature. However, when looking at individuals as leaders, many respondent-nominated leaders would not be identified using SNA because they are poorly connected. Also, many individuals who were not nominated would have been considered leaders because they are well connected. Further examining these results did not indicate why there is such a difference between the SNA-identified and respondent-nominated leaders. Conclusions: While these two methods identify some of the same individuals as leaders, there are many differences between the two methods. Using just one method may not be adequate for ensuring that suitable individuals are selected to lead these projects. We recommend multiple methods when selecting leaders.