ERIC Number: EJ1179103
Record Type: Journal
Publication Date: 2018-Jun
Abstractor: As Provided
Subgrouping Autism Based on Symptom Severity Leads to Differences in the Degree of Convergence between Core Feature Domains
Whitten, Allison; Unruh, Kathryn E.; Shafer, Robin L.; Bodfish, James W.
Journal of Autism and Developmental Disorders, v48 n6 p1908-1919 Jun 2018
Existing models of autism spectrum disorder (ASD) disagree as to whether the core features should be conceptualized as convergent (related) or divergent (unrelated), and the few previous studies addressing this question have found conflicting results. We examined standardized parent ratings of symptoms from three domains (social, communication, repetitive behaviors) in large samples of typically developing children, children with ASD, and ASD subgroups. Our results suggest that the most evidence for divergence lies in typically developing children and lower severity ASD cases, while more evidence for convergence is found in a subset of cases with more severe impairment on any core feature. These results highlight the importance of subgrouping ASD given the degree of phenotypic heterogeneity present across the autism spectrum.
Descriptors: Autism, Symptoms (Individual Disorders), Pervasive Developmental Disorders, Genetics, Models, Parent Attitudes, Classification, Behavior Problems, Communication Skills, Interpersonal Competence, Children, Comparative Analysis, Severity (of Disability)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Sponsor: National Institute of Mental Health (DHHS/NIH); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH)
Authoring Institution: N/A
Grant or Contract Numbers: R01MH073402; R01HD082127