This study reports the evaluation of four positive psychology assessments for use in clinical, education, and research settings with individuals in Ghana, Africa. The analyses attempted to identify validity evidence for internal structure and relationships with related variables for the Satisfaction with Life Scale (SLS; Diener et al. "Journal of Personality Assessment," "49," 71-75, 1985), General Mattering Scale (GMS; Marcus 1991), Short Grit Scale (GS; Duckworth and Quinn "Journal of Personality Assessment," "9," 166-174, 2009), and Brief Resilience Scale (BRS; Smith et al. "International Journal of Behavioral Medicine," "15," 194-200, 2008). The data yielded from 657 Ghanaian participants indicated factor structures ranging from a strong model fit (SLS and GMS) to an acceptable fit following modifications to factor structure (GS and BRS), while evidence based on relationships to related variables was convincing. Implications for use of these assessments and for future research are discussed.