Student demand for distance learning, changing student demographics, and low retention compel institutions of higher education to develop alternative forms of academic support that can effectively serve the increasingly diverse needs of students. Videoconferencing provides institutions with the capacity to provide interactive real-time academic support that can successfully accommodate these needs. This article discusses the technical, pedagogical, staffing, training, and marketing factors that were important in the development and management of an online academic support program delivered synchronously through videoconferencing to students in high-risk Science, Technology, Engineering, and Mathematics (STEM) courses. The factors emerged from a mixed-method study that showed the efficacy of the online academic support program and identified influences that affected student adoption of academic support through videoconferencing.