The objective of the present study was to better understand a relatively under-researched topic, namely, undergraduate students' attitudes towards mistakes and how their attitudes relate to academic achievement. A series of online surveys were administered to a sample of 207 first- and second-year undergraduate students. Using structural equational modelling, a hypothesised model was proposed to evaluate the following four research questions: (1) What is the effect of students' trust in their instructor on students' achievement goals? (2) What is the relationship between students' achievement goals and their attitudes towards mistakes? (3) Is students' attitudinal behaviour towards mistakes predictive of their perception of feedback? (4) Is students' openness to discussing mistakes (ODM) and attitudinal behaviours predictive of their academic achievement? Both direct and indirect effects were found. Direct effects indicated that students' trust in their instructor predicted achievement goals, students' achievement goals differentially predicted attitudes towards mistakes, students' ODM predicted perceptions of feedback, and students' attitudinal behaviours predicted academic achievement. Students' trust in their instructor and achievement goals had indirect effects on students' achievement.