A 14 week undergraduate course on laboratory safety was developed at the University of Pittsburgh. The first segment of the course consists of a series of lectures intended to increase the students' knowledge and appreciation of safety. In the second segment, experts from both academia and industry present and discuss case studies on specialized issues in laboratory safety. The course culminates with interactive exercises, written assignments, and student capstone projects, which reinforce an understanding of the course principles and encourage undergraduates to take leadership and ownership of safety. The creativity exhibited through the student projects and the results of a post-semester survey suggest that the course inspired students to take a greater role in promoting safety culture.