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ERIC Number: EJ1175822
Record Type: Journal
Publication Date: 2018-Apr
Pages: 10
Abstractor: As Provided
ISSN: ISSN-0021-9584
Reinforcing Mass Spectrometry Concepts through an Undergraduate Laboratory Exercise Utilizing a Direct Analysis in Real Time Enabled Mass Spectrometer
Beck, Rachel C.; Erdmann, Mitzy A.
Journal of Chemical Education, v95 n4 p652-661 Apr 2018
Identification and quantification of an unknown illicit drug (cocaine) from both simulated drug paraphernalia and simulated urine can be achieved via direct analysis in real time (DART) triple quadrupole linear ion trap (QTRAP) mass spectrometry (MS). We describe a novel, hands-on laboratory activity which utilizes the recent DART technology interfaced with a tandem mass spectrometer for the purpose of integrating recent technology into a quantitative analysis course, reinforcing chemical concepts, improving critical thinking and written communication skills, and providing a context for real-life analyses. The hands-on laboratory activity requires students to use good laboratory practice, perform common laboratory calculations, and think critically to perform both qualitative and quantitative analyses and answer real-life forensic questions. Assessments include prelaboratory activity questions, observations during the activity, postlaboratory activity written report, and anonymous summative activity.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Alabama (Birmingham)
Grant or Contract Numbers: N/A