The article considers topical issues of a new form of interaction of educational organizations within a regional education system--networking cooperation by means of distance learning technologies. The purpose of the research is to develop a networking cooperation model of educational organizations through distance learning technologies and its methodical support within a regional education system based on the principles of openness, regionalization, integrity, productivity and technological effectiveness. The methodological basis of the research is comprised of the main ideas of systematic, technological and activity approaches. The model provides educational organizations with an opportunity to use it in the geographically remote regions. This provides for a continual cooperation of educational organizations at the regional level, creates an integrated learning environment, expands a resource potential of educational organizations and contributes to the improvement of education quality.