Now visualization courses have been taught at universities around the world. Keeping students motivated and actively engaged in this course can be a challenging task. In this paper we introduce our developed interactive learning system called VisMis (Visualization and Multi-modal Interaction System) for postgraduate scientific visualization course at Beijing Normal University. We develop it following the Great Didactic from Comenius and the theory of constructivism on constructing the visual and interactive learning environment to support and challenge the student's learning. We give a report on our proprietary system including its educational objective, volume visualization module, multi-modal interaction module, and CUDA implementation etc. By the evaluation, we conclude that VisMis is an innovative platform for volume visualization with novel transfer function design and multi-modal interaction. It has more advantage in easiness, speed, layer control, interaction, etc.