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ERIC Number: EJ1175297
Record Type: Journal
Publication Date: 2018-May
Pages: 7
Abstractor: As Provided
ISSN: ISSN-0162-3257
Association of Autism Spectrum Disorders and Inflammatory Bowel Disease
Lee, Maunoo; Krishnamurthy, Jayasree; Susi, Apryl; Sullivan, Carolyn; Gorman, Gregory H.; Hisle-Gorman, Elizabeth; Erdie-Lalena, Christine R.; Nylund, Cade M.
Journal of Autism and Developmental Disorders, v48 n5 p1523-1529 May 2018
Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD. Children with ASD were more likely to meet criteria for Crohn's disease (CD) and Ulcerative colitis (UC) compared to controls. This higher prevalence of CD and UC in children with ASD compared to controls confirms the association of ASD with IBD. [This project has been presented as a poster format at DDW (Digestive Disease Week) conference in Chicago, IL on May 9, 2017.]
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: Congressionally Directed Medical Research Programs (CDMRP) (DOD)
Authoring Institution: N/A
Grant or Contract Numbers: W81XWH1220066